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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1A1L
All Species:
29.39
Human Site:
Y32
Identified Species:
46.19
UniProt:
Q8N752
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N752
NP_660204.1
337
39086
Y32
S
G
S
F
G
D
V
Y
L
G
I
T
T
T
N
Chimpanzee
Pan troglodytes
XP_522662
337
39019
Y32
S
G
S
F
G
D
V
Y
L
G
I
T
T
T
N
Rhesus Macaque
Macaca mulatta
XP_001085343
337
38964
Y32
S
G
S
F
G
D
V
Y
L
G
I
T
T
T
N
Dog
Lupus familis
XP_867638
336
38749
Y32
S
G
S
F
G
D
I
Y
L
A
I
N
I
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
K38
S
G
E
E
V
A
I
K
L
E
C
V
K
T
K
Rat
Rattus norvegicus
P97633
325
37477
I31
G
S
G
S
F
G
D
I
Y
L
A
I
N
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P67962
337
38882
Y32
S
G
S
F
G
D
I
Y
L
A
I
N
I
T
N
Frog
Xenopus laevis
Q5BP74
415
47421
K38
A
S
E
E
V
A
I
K
L
E
C
V
K
T
K
Zebra Danio
Brachydanio rerio
Q7T2E3
403
46225
K38
T
G
E
E
V
A
I
K
L
E
C
V
K
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54367
337
39516
Y35
S
G
S
F
G
D
I
Y
L
G
M
S
I
Q
S
Honey Bee
Apis mellifera
XP_393612
350
40282
Y36
S
G
S
F
G
D
I
Y
L
G
I
N
I
S
N
Nematode Worm
Caenorhab. elegans
P42168
341
39018
S33
S
F
G
D
I
Y
V
S
I
N
V
T
N
G
E
Sea Urchin
Strong. purpuratus
XP_786391
348
40003
Y46
S
G
S
F
G
D
I
Y
L
G
I
N
I
H
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
K38
T
N
E
E
L
A
I
K
L
E
N
V
K
T
K
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
V81
E
G
E
Y
N
A
M
V
I
D
L
L
G
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.9
90.5
N.A.
54.5
88.1
N.A.
N.A.
90.5
53.9
56.5
N.A.
70.6
76.2
75.3
74.1
Protein Similarity:
100
99.6
99.4
94.3
N.A.
66.1
91
N.A.
N.A.
94.6
66
68.2
N.A.
81.3
84
82.1
84.2
P-Site Identity:
100
100
100
73.3
N.A.
26.6
0
N.A.
N.A.
73.3
13.3
20
N.A.
60
73.3
20
73.3
P-Site Similarity:
100
100
100
80
N.A.
33.3
0
N.A.
N.A.
80
26.6
33.3
N.A.
86.6
86.6
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
39.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.7
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
34
0
0
0
14
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% C
% Asp:
0
0
0
7
0
54
7
0
0
7
0
0
0
0
0
% D
% Glu:
7
0
34
27
0
0
0
0
0
27
0
0
0
0
7
% E
% Phe:
0
7
0
54
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
74
14
0
54
7
0
0
0
40
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
7
0
60
7
14
0
47
7
34
7
0
% I
% Lys:
0
0
0
0
0
0
0
27
0
0
0
0
27
0
27
% K
% Leu:
0
0
0
0
7
0
0
0
80
7
7
7
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% M
% Asn:
0
7
0
0
7
0
0
0
0
7
7
27
14
0
47
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
67
14
54
7
0
0
0
7
0
0
0
7
0
7
14
% S
% Thr:
14
0
0
0
0
0
0
0
0
0
0
27
20
60
7
% T
% Val:
0
0
0
0
20
0
27
7
0
0
7
27
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
7
0
54
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _